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Table 4 Analytical goals for imprecision, bias, total error allowable (TEa) for p < 0.01 and p < 0.05, reference change value (RCV), Reliability coefficient (R), index of individuality (II), and index of heterogeneity (IH) for five lymphocyte phenotypes

From: Biological variation of immunological blood biomarkers in healthy individuals and quality goals for biomarker tests

Biomarker Phenotype

Analytical goal for precision (%)

bias (%)

TE a (%)

RCV (%)

R

II

IH

p < 0.05

p < 0.01

P < 0.05

CD3 (T cells)

1.8

2.8

5.8

7.0

11.1

0.89

0.34

0.06

CD4

3.1

5.4

10.5

12.6

19.2

0.90

0.33

0.11

CD8

3.4

9.0

14.6

16.8

19.8

0.96

0.20

0.11

CD19 (B

8.7

9.1

23.4

29.4

49.6

0.76

0.56

0.28

cells) CD56/16 (NK cells)

11.5

10.9

29.9

37.7

65.7

0.71

0.64

0.37