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Table 2 IgA and/or IgG MT10.3:MPT64 Pleural Fluid (PF) and/or sera dilutions combination results with other antigens or ADA results that provide the best sensibility (S) and specificity (Sp) for pleural tuberculosis patients (PLTB)

From: IgA and IgG antibody detection of mycobacterial antigens in pleural fluid and serum from pleural tuberculous patients

MT10.3:MPT64 Combination results (sample dilutions)/

PLTB (N = 29)

N. Positive

S (%)

OPL (N = 39)

N. Negative

Sp (%)

Pleural Fluid IgA

 (1:50) / PPE59 (1:100)

27 (93.1)

36 (92.3)

 (1:100)/ PPE59 (1: 100)

24 (82.7)

37 (94.8)

(1:200) / PPE59 (1:100);

26 (89.6)

37 (94.8)

(1:50) / MPT64 (1:100);

(1:50) / F2 (1:50)

 (1:400)/ PPE59 (1:100);

26 (89.6)

36 (92.3)

 (1:50) or /(1:200) or /(1:400) / MT10.3 (1:100)

 (1:800) / PPE59 (1:100);

21 (72.4)

36 (92.3)

 (1:100) / MT10.3 (1:100)

 (1:100) / MPT64 (1:100)

20 (68.9)

36 (92.3)

 (1:200) / MPT64 (1:100) or / F2 (1:50) or / MT10.3:MPT64.serum1.50

25 (86.2)

36 (92.3)

 (1:400) / MPT64 (1:100) or / F2 (1:50)

24 (82.7)

36 (92.3)

 (1:100) / F2 (1:50)

22 (75.8)

36 (92.3)

 (1:50) / MT10.3-MPT64.serum1.50

26 (93.1)

35 (89.7)

 (1:1000) / MT10.3-MPT64.serum1.50

19 (65.5)

36 (92.3)

Serum IgA

 (1.50) / MPT64 (1:50)

13 (44.8)

36 (92.3)

 (1.50) / MPT64 (1:200)

14 (48.2)

36 (92.3)

Serum IgG

 (1:50) / F2 (1:400)

15 (51.7)

36 (92.3)

 (1:50) / F2 (1:800 or 1:1600)

16 (55.1)

36 (92.3)

Pleural Fluid IgA/IgG

 (1:50)/ MT10.3:MPT64 (1:200)

27 (93.1)

36 (92.3)

Pleural Fluid IgA

 (1:50) / F2 (1:50)/ ADA

28 (96.6%)

36 (92.3%)

  1. OPL other non-tuberculous pleurisy
  2. Boldface: represents the combinatory test results of best sensitivities and specificity