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Table 2 IgA and/or IgG MT10.3:MPT64 Pleural Fluid (PF) and/or sera dilutions combination results with other antigens or ADA results that provide the best sensibility (S) and specificity (Sp) for pleural tuberculosis patients (PLTB)

From: IgA and IgG antibody detection of mycobacterial antigens in pleural fluid and serum from pleural tuberculous patients

MT10.3:MPT64 Combination results (sample dilutions)/ PLTB (N = 29)
N. Positive
S (%)
OPL (N = 39)
N. Negative
Sp (%)
Pleural Fluid IgA
 (1:50) / PPE59 (1:100) 27 (93.1) 36 (92.3)
 (1:100)/ PPE59 (1: 100) 24 (82.7) 37 (94.8)
(1:200) / PPE59 (1:100); 26 (89.6) 37 (94.8)
(1:50) / MPT64 (1:100);
(1:50) / F2 (1:50)
 (1:400)/ PPE59 (1:100); 26 (89.6) 36 (92.3)
 (1:50) or /(1:200) or /(1:400) / MT10.3 (1:100)
 (1:800) / PPE59 (1:100); 21 (72.4) 36 (92.3)
 (1:100) / MT10.3 (1:100)
 (1:100) / MPT64 (1:100) 20 (68.9) 36 (92.3)
 (1:200) / MPT64 (1:100) or / F2 (1:50) or / MT10.3:MPT64.serum1.50 25 (86.2) 36 (92.3)
 (1:400) / MPT64 (1:100) or / F2 (1:50) 24 (82.7) 36 (92.3)
 (1:100) / F2 (1:50) 22 (75.8) 36 (92.3)
 (1:50) / MT10.3-MPT64.serum1.50 26 (93.1) 35 (89.7)
 (1:1000) / MT10.3-MPT64.serum1.50 19 (65.5) 36 (92.3)
Serum IgA
 (1.50) / MPT64 (1:50) 13 (44.8) 36 (92.3)
 (1.50) / MPT64 (1:200) 14 (48.2) 36 (92.3)
Serum IgG
 (1:50) / F2 (1:400) 15 (51.7) 36 (92.3)
 (1:50) / F2 (1:800 or 1:1600) 16 (55.1) 36 (92.3)
Pleural Fluid IgA/IgG
 (1:50)/ MT10.3:MPT64 (1:200) 27 (93.1) 36 (92.3)
Pleural Fluid IgA
 (1:50) / F2 (1:50)/ ADA 28 (96.6%) 36 (92.3%)
  1. OPL other non-tuberculous pleurisy
  2. Boldface: represents the combinatory test results of best sensitivities and specificity