Fig. 4

KEGG and GSEA. a. Significantly enriched activated and suppressed KEGG pathways. The vertical items are the names of KEGG terms, and the length of horizontal graph represents the gene ratio. The depth of the color represents the adjusted p-value. The area of circle in the graph means gene counts. b. GSEA-based KEGG-enrichment plots of representative gene sets from activated pathway: Epstein–Barr virus infection. c. GSEA-based KEGG-enrichment plots of representative gene sets from suppressed pathway: Biosynthesis of amino acids. KEGG and GSEA analysis was performed by using R package clusterProfiler (version 3.8.1); R package DOSE (version 3.6.1); and R package org. Hs.eg.db (version 3.6.0). The analysis results were visualized by using R package Enrichplot (version 1.2.0)