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Fig. 2 | BMC Immunology

Fig. 2

From: Foxp3+Helios+ regulatory T cells are associated with monocyte subsets and their PD-1 expression during acute HIV-1 infection

Fig. 2

Perturbations of PD-1 expression on the three monocyte subsets in HIV-1-infected patients. The gating strategy for PD-1 expression on monocyte subsets is indicated (a). The MFI of PD-1 on CD14++CD16 (b), CD14++CD16+ (c), and CD14+CD16++ (d) monocytes were analyzed by flow cytometry in HC, AHI, CHI&ART-, and CHI&ART+ patients. Correlations between the MFI of surface PD-1 on CD14++CD16 and CD4 T-cell counts (e) as well as the CD4/CD8 ratio (f) in chronic HIV-1-infected cART-naïve patients. Correlation between MFI of surface PD-1 on CD14+CD16++ and the CD4/CD8 ratio (g) in acute HIV-1-infected patients. The box marks the min and max values, and horizontal lines depict median values in (b), (c) and (d). All p values were calculated using an ANOVA, Student’s t-test or the Mann-Whitney U test, and Spearman’s correlation coefficient

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