Fig. 3

Correlations between the frequency of Foxp3⁺Helios⁺ Treg cells and monocyte subsets and their PD-1 expression in HIV-1-infected individuals. Correlation between the frequency of Foxp3⁺Helios⁺CD45RA⁺ Treg cells and CD14⁺⁺CD16⁺ monocyte subsets (a), PD-1 density on CD14⁺⁺CD16⁺ monocytes (b), and PD-1 density on CD14⁺CD16⁺⁺ monocytes (c) during acute HIV-1 infection. Correlation between the frequency of Foxp3⁺Helios⁺CD45RO⁺ Treg cells and CD14⁺⁺CD16⁺ monocyte subsets (d), PD-1 density on CD14⁺⁺CD16⁺ monocytes (e), and PD-1 density on CD14⁺CD16⁺⁺ monocytes (f) during acute HIV-1 infection. Correlations were analyzed by calculating Spearman’s correlation coefficient