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Table 1 Characteristics of HIV-1-infected patients and healthy controls

From: Foxp3+Helios+ regulatory T cells are associated with monocyte subsets and their PD-1 expression during acute HIV-1 infection

 

Healthy controls

Acute HIV-1-infected patients

Chronic cART-naïve HIV-1-infected patients

Chronic HIV-1-infected patients with cART

Cases, no

36

36

28

32

Age (years)

28.3 (21–46)

29.5 (20–48)

28.7 (20–47)

29.2 (21–46)

HIV-RNA (copies/ml)

NA

316,924.7 (2409–6,313,483)

26,934.1 (567–147,548)

TND

CD4 (cells/μl)

748 (328–1506)

470 (215–762)

311 (134–638)

672 (318–1280)

CD4/CD8 ratio

1.13 (0.43–2.16)

0.49 (0.1–1.13)

0.33 (0.11–0.68)

0.75 (0.29–1.57)

  1. Data are presented as the means with ranges
  2. Abbreviations: cART combined antiretroviral therapy, NA not available, TND target not detected