From: Subsets of mononuclear phagocytes are enriched in the inflamed colons of patients with IBD
Infliximimab Non-Response | Vedolizumab Non-Response | ||||||
---|---|---|---|---|---|---|---|
UC (GSE16879) | CD (GSE16879) | UC (GSE73661) | UC (GSE73661) | ||||
Cell type | AUC | Cell type | AUC | Cell type | AUC | Cell type | AUC |
Macrophages.M1 | 0.84 | Monocytes | 0.99 | Tregs | 0.84 | Monocytes | 0.7 |
aDC | 0.84 | Neutrophils | 0.98 | Tgd.cells | 0.83 | Mast.cells | 0.67 |
Tregs | 0.81 | Macrophages.M1 | 0.83 | CD4.naive. T.cells | 0.82 | Macrophages.M1 | 0.64 |
Tgd.cells | 0.79 | aDC | 0.83 | Th2.cells | 0.8 | Macrophages | 0.59 |
Monocytes | 0.78 | pDC | 0.81 | CD8.Tcm | 0.77 | Th1.cells | 0.58 |
CD8.Tcm | 0.77 | CD8.Tem | 0.77 | CD4.Tem | 0.77 | DC | 0.58 |
Th2.cells | 0.74 | Macrophages | 0.75 | CD4.memory. T.cells | 0.76 | Neutrophils | 0.58 |
CD4.T.cells | 0.73 | B.cells | 0.73 | Macrophages.M1 | 0.75 | Th2.cells | 0.58 |
Neutrophils | 0.73 | CD4.Tcm | 0.72 | CD4.Tcm | 0.74 | aDC | 0.58 |
CD4.Tcm | 0.71 | Tregs | 0.71 | aDC | 0.73 | Basophils | 0.55 |