Fig. 2
The peripheral blood concentrations of total leukocytes (a), CD14+ monocytes (b), classical (c), intermediate (d) and non-classical (e) monocytes in auto-transplanted myeloma patients. We estimated the cell concentrations by flow cytometry. The left parts of each panel show a comparison of peripheral blood levels before versus 2 days after the conditioning melphalan therapy (day − 2 versus day 0; Table 1, patients 7–9, 12–18). The middle parts show a comparison of levels at the time of transplantation (day 0) versus the levels during the period of severe posttransplant melphalan-induced pancytopenia with neutrophils < 0.2 × 109/L and thrombocyte transfusion dependency (tested 6–8 days posttransplant; Table 1, patients 14, 15, 17, 22, 24). The right panel show the comparison of peripheral blood levels during the severe pancytopenia versus the levels during initial hematopoietic and immunological reconstitution (tested 10–12 days posttransplant with increasing neutrophils > 0.2 × 109/L and thrombocyte transfusion independence; Table 1 patients 15, 17, 18, 22–24). The Wilcoxon’s test for paired samples was used for statistical analyses and significant p-values are indicated in the figure (ASCT, autologous stem cell transplantation)