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Table 1 Evaluation of the protective efficacy of the LACV and unformulated VCUSM14P in the RITARD model

From: Immunogenicity and protective efficacy of a live, oral cholera vaccine formulation stored outside-the-cold-chain for 140 days

Challenge outcome

Rabbit orally vaccinated with the LACV (n = 3)

Rabbit orally vaccinated with the VCUSM14P strain (n = 3)

Unvaccinated rabbit (n = 3)

Mild diarrhoea

0 of 3

0 of 3

0 of 3

Severe diarrhoea

0 of 3

0 of 3

3 of 3

Intestinal haemorrhage

0 of 3

0 of 3

3 of 3

Animal death

0 of 3

0 of 3

3 of 3

Percent mortality

0%

0%

100%

Fluid accumulation in the small intestine

No

No

Yes