TY - JOUR AU - Higashioka, Kazuhiko AU - Ota, Yuri AU - Maehara, Takashi AU - Moriyama, Masafumi AU - Ayano, Masahiro AU - Mitoma, Hiroki AU - Akahoshi, Mitsuteru AU - Arinobu, Yojiro AU - Horiuchi, Takahiko AU - Nakamura, Seiji AU - Akashi, Koichi AU - Niiro, Hiroaki PY - 2020 DA - 2020/06/01 TI - Association of circulating SLAMF7+Tfh1 cells with IgG4 levels in patients with IgG4-related disease JO - BMC Immunology SP - 31 VL - 21 IS - 1 AB - Follicular helper CD4+ T (Tfh) cells have a critical role in IgG4 production by B cells in IgG4-related disease (IgG4-RD). Recent studies including ours showed that SLAMF7+CD4+ T cells are an important pathological driver of IgG4-RD. In this study, we have sought to elucidate a relationship between helper CD4+ T (Th), particularly Tfh, cells and SLAMF7+ CD4+ T cells in IgG4-RD. SN - 1471-2172 UR - https://doi.org/10.1186/s12865-020-00361-0 DO - 10.1186/s12865-020-00361-0 ID - Higashioka2020 ER -