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Fig. 4 | BMC Immunology

Fig. 4

From: Association of circulating SLAMF7+Tfh1 cells with IgG4 levels in patients with IgG4-related disease

Fig. 4

Correlation of SLAMF7+ activated cTfh1 cells with serum IgG4 titer and expression of IL-21 and IL-10 mRNA in Tfh1 subsets in IgG4-RD. a Correlation of serum titers of IgG4 with the number of Th1, activated Tfh, activated Tfh1 and activated Tfh2 cells in IgG4-RD patients. b Correlation of serum titers of IgG4 with the number of SLAMF7+ Th1, PD-1− Tfh1, SLAMF7−PD-1+ Tfh1 and SLAMF7+PD-1+ Tfh1 cells in IgG4-RD patients. c Comparison of levels of IL-21 and IL-10 mRNA in PD-1− Tfh1 cells, SLAMF7−PD-1+ Tfh1 cells and SLAMF7+PD-1+ Tfh1 cells in the peripheral blood of patients with IgG4-RD (n = 11). d Comparison of levels of Bcl-6 and Blimp-1 mRNA in PD-1− Tfh1 cells, SLAMF7−PD-1+ Tfh1 cells and SLAMF7+PD-1+ Tfh1 cells in patients with IgG4-RD (n = 7). * indicates p < 0.05, ** indicates p < 0.01

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