TY - JOUR AU - Niu, Hong-Qing AU - Zhao, Xiang-Cong AU - Li, Wei AU - Xie, Jian-Fang AU - Liu, Xiao-Qing AU - Luo, Jing AU - Zhao, Wen-Peng AU - Li, Xiao-Feng PY - 2020 DA - 2020/08/03 TI - Characteristics and reference ranges of CD4+T cell subpopulations among healthy adult Han Chinese in Shanxi Province, North China JO - BMC Immunology SP - 44 VL - 21 IS - 1 AB - Immunophenotyping of blood lymphocytes is an essential tool to evaluate the immune function of patients with immunodeficiency or autoimmunity. Predominately identified CD4+T cell subsets, Th1, Th2, Th17, as well as regulatory T (Treg) cells, play crucial roles in several immunological and pathological conditions. Considering the variations in cell counts among populations and ethnicities, specific CD4+T cell subset reference values need to be locally established to enable meaningful comparisons and accurate data interpretation in clinical and research settings. Therefore, the aim of this study was to establish distributions and reference ranges for blood CD4+T cell subpopulations in age- and sex-balanced healthy adults of a Han Chinese population in Shanxi Province, North China. SN - 1471-2172 UR - https://doi.org/10.1186/s12865-020-00374-9 DO - 10.1186/s12865-020-00374-9 ID - Niu2020 ER -