TY - JOUR AU - Lee, Mi Jin AU - Yun, Su Jin AU - Lee, Bokyoung AU - Jeong, Eun AU - Yoon, Gyesoon AU - Kim, Kyongmin AU - Park, Sun PY - 2020 DA - 2020/08/20 TI - Association of TIM-3 expression with glucose metabolism in Jurkat T cells JO - BMC Immunology SP - 48 VL - 21 IS - 1 AB - T cell activation is associated with increase in glycolysis and glutaminolysis. T cell immunoglobulin and mucin domain containing protein-3 (TIM-3), a T cell surface molecule, downregulates T cell activation and leads to insufficient immunity in cancer and chronic infection. TIM-3 regulates T cell activation possibly through alterations in metabolism; however, the relationship between TIM-3 expression and T cell metabolic changes has not been well studied. SN - 1471-2172 UR - https://doi.org/10.1186/s12865-020-00377-6 DO - 10.1186/s12865-020-00377-6 ID - Lee2020 ER -