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Fig. 3 | BMC Immunology

Fig. 3

From: Association of TIM-3 expression with glucose metabolism in Jurkat T cells

Fig. 3

Glucose consumption and lactate release in cells expressing TIM-3 with deletion of cytoplasmic tail. Glucose consumption (a) and lactate release (b) in control cells (JLV), TIM-3 cytoplasmic tail deletional mutant cells (JLct36, JLct43, JLct54, and JLct64) and cells expressing full-length TIM-3 (JLT3) in the absence (−) or presence (+) of PMA (25 ng/ml) and Iono (10 μM) for 6 h. Data represent two independent experiments performed in sextuplicate. Data are mean ± SD. P/I: PMA and Iono. *: P < 0.05

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