T2D compared to control group | ||||||
Patient or population: Adult individuals (> 18 years) Exposure: T2D Comparison: Non-diabetic (control) Outcome: Levels of peripheral blood natural killer cells | ||||||
Outcomes | Anticipated absolute effects* (95% CI) | Relative effect (95% CI) | № of participants (studies) | Certainty of the evidence (GRADE) | Comments | |
Risk with Control | Risk with T2D | |||||
Levels of peripheral blood natural killer cells | The mean levels in the exposure group was 0.03 higher (−3.20, 3.26) | – | 1164 (6 observational studies) | ⨁⨁oo LOW | ||
*The risk in the intervention group (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI). CI: Confidence interval; MD: Mean difference; OR: Odds ratio; NE: Not estimable | ||||||
GRADE Working Group grades of evidence High certainty: We are very confident that the true effect lies close to that of the estimate of the effectModerate certainty: We are moderately confident in the effect estimate: The true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different Low certainty: Our confidence in the effect estimate is limited: The true effect may be substantially different from the estimate of the effectVery low certainty: We have very little confidence in the effect estimate: The true effect is likely to be substantially different from the estimate of effect |