Interleukin 4 gene polymorphism (−589C/T) and the risk of asthma: a meta-analysis and met-regression based on 55 studies

Table 4 Meta-regression analyses of potential source of heterogeneity

Heterogeneity Factors		Coefficient	SE	T	P-value	95% CI
Heterogeneity Factors		Coefficient	SE	T	P-value	UL	LL
Publication Year	Dominant model	0.035	0.041	0.85	0.40	−0.048	1.119
	Recessive model	0.140	0.036	3.81	0.07	−0.066	0.213
	Allelic model	0.035	0.022	1.58	0.11	−0.009	0.080
	TT vs. CC	0.123	0.064	1.91	0.06	−0.006	0.254
	CT vs. CC	0.020	0.035	0.58	0.56	−0.050	0.090
continent	Dominant model	−0.238	0.265	−0.90	0.37	−0.772	0.294
	Recessive model	0.022	0.274	0.08	0.93	−0.530	0.574
	Allelic model	−0.116	0.146	−0.79	0.43	−0.410	0.177
	AA vs. CC	−0.096	0.435	−0.22	0.82	−0.973	0.780
	CA vs. CC	−0.265	0.209	−1.27	0.21	−0.685	0.154
Genotyping methods	Dominant model	−0.137	0.241	−0.57	0.57	−0.621	0.346
	Recessive model	0.382	0.232	1.65	0.10	−0.084	0.849
	Allelic model	0.039	0.130	0.30	0.76	−0.221	0.300
	TT vs. CC	0.056	0.388	0.14	0.88	−0.726	0.838
	CT vs. CC	−0.114	0.199	−0.57	0.57	−0.515	0.287

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