Table 2 Calculation of the false-positive report probability (FPRP) for the risk associations of sex and rs2232365 polymorphism to chronic diseases and their clinical and pathological profiles
Associations | OR (IC 95%) | p | Statistical power | Prior probability | |||||
|---|---|---|---|---|---|---|---|---|---|
0.25 | 0.1 | 0.01 | 0.001 | 0.0001 | 0.00001 | ||||
Sexual associations | |||||||||
HTLV-1: | |||||||||
Female vs Male | 1.91 (1.10–3.33) | 0.03 | 0.1971 | 0.2913 | 0.5331 | 0.9113 | 0.9913 | 0.9990 | 0.9999 |
CAD: | |||||||||
Female vs Male | 1.53 (1.08–2.16) | 0.02 | 0.4552 | 0.1101 | 0.2557 | 0.7558 | 0.9717 | 0.9968 | 0.9997 |
Genetic associations | |||||||||
HTLV-1: | |||||||||
(Males) T vs C | 0.36 (0.14–0.92) | 0.05 | 0.0990 | 0.5441 | 0.7683 | 0.9676 | 0.9970 | 0.9997 | 1.0000 |
CVLD (F0-F1): | |||||||||
(Males) T vs C | 4.18 (1.13–15.4) | 0.05 | 0.0617 | 0.6480 | 0.8364 | 0.9787 | 0.9980 | 0.9997 | 0.9999 |
Multiple regression associations | |||||||||
HTLV-1: | |||||||||
Sex (Female vs Male) | 2.11 (1.18–3.75) | 0.02 | 0.1224 | 0.2432 | 0.4717 | 0.8893 | 0.9889 | 0.9986 | 0.9999 |
(Males) T vs C | 0.43 (0.20–0.95) | 0.04 | 0.1391 | 0.4885 | 0.7262 | 0.9598 | 0.9962 | 0.9996 | 0.9999 |
CAD: | |||||||||
Sex (Female vs Male) | 1.44 (0.95–2.19) | 0.02 | 0.5757 | 0.3556 | 0.6052 | 0.9324 | 0.9935 | 0.9993 | 0.9999 |
CVLD (F0-F1): | |||||||||
(Males) T vs C | 1.11 (0.43–2.90) | 0.05 | 0.7306 | 0.8037 | 0.9192 | 0.9903 | 0.9991 | 0.9999 | 0.9999 |