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Fig. 7 | BMC Immunology

Fig. 7

From: Enhancement of Zika virus infection by antibodies from West Nile virus seropositive individuals with no history of clinical infection

Fig. 7

Non-neutralizing ZIKV antibodies cause enhancement of ZIKV infection at higher concentration without virus neutralization. a Vero cells were infected with ZIKV RVPs in the presence of different dilutions of ZIKV antibodies and number of GFP positive cells analyzed 72 h post infection. Percent infection was determined as above. b K562 cells were infected with ZIKV RVPs in the presence different dilutions of ZIKV antibodies and number of GFP positive cells analyzed 48 h post infection. Percent ADE was determined as above. c Pooled average of data from all WNV seropositive donors was plotted for neutralization of ZIKV and WNV infection. d Pooled average of data from all WNV seropositive donors was plotted for enhancement of ZIKV and WNV infection

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