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Fig. 8 | BMC Immunology

Fig. 8

From: Enhancement of Zika virus infection by antibodies from West Nile virus seropositive individuals with no history of clinical infection

Fig. 8

Prevalence of cross reactive E antibodies correlates with ZIKV neutralization and enhancement. a Stable cell line expressing Zika CprME-NS2B3 was radiolabeled with [35S]Met/Cys and cell lysates immunoprecipitated with Protein-A agarose beads coated with different WNV+ sera samples. Samples were resolved on and SDS-PAGE gel followed by PhosphorImager analysis. b Correlation analysis of Envelope band intensity with serum dilution causing 50% ZIKV neutralization. c Correlation analysis of Envelope band intensity with dilution of peak ZIKV ADE. Curves were fitted using GraphPad prism and simple linear regression. P values were obtained from two-tailed t test

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BMC Immunology

ISSN: 1471-2172

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