Fig. 6

D-mannose decreased the number of T_EM and T_FH cells and increased the frequency of Treg cells in recipient mice in the cGVHD model. Frequency and numbers of recipient T_EM (a-b), T_FH (c-d) and Treg (e-f) cells in the mLN. Representative FACS plots of donor (CD45.2⁺) and recipient (CD45.2⁻) cells are shown on the left. Mean ± S.E.M of n = 4 per group compared with t tests. *: p < 0.05, **: p < 0.01