Dysregulation of TNF-α and IFN-γ expression is a common host immune response in a chronically infected mouse model of melioidosis when comparing multiple human strains of Burkholderia pseudomallei

Table 3 Chronically infected mice show elevated antibody levels after infection with clinical strains of B. pseudomallei

^a Antibody titers were done in triplicate for each mouse at least once, and titers are reported as geometric mean with geometric SEM
^b There was a total of 63 sera from exposed BALB/c mice. The number in parentheses represents the number of mice in each group
^c The number 50 was used for calculation of statistics although the antibody titers were less than 50
^d The significant levels are derived from comparing antibody levels for specific groups with those of naïve (Gp 1) mice
^e The exposure strain and number of mice (in parenthesis) in each group as follows: Gp. 2, MSHR5855 (7), HBPUB10134a (8), 406e (3), MSHR668 (5), MSHR5848 (6), K96243 (3); Gp. 3, 406e (1), 1026b (1), MSHR668 (1), MSHR5848 (1), MSHR305 (1), K96243 (1), 1106a (2); Gp. 4, MSHR5855 (1), 406e (2), 1026b (3), MSHR668 (1), MSHR5848 (1), MSHR5858 (4), MSHR305 (3), K96243 (2), 1106a (6)

ISSN: 1471-2172