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Table 1 Characteristics of individual studies included in the meta-analysis

From: Inducible nitric oxide synthase and systemic lupus erythematosus: a systematic review and meta-analysis

StudyStudy designSample size (SLE/control)Gender of SLE(F/M)Mean age of SLE(y)Criteria of SLE diagnosisType of tissue/cell used in studiesCharacteristics of controls
Belmont 1997 [32]Case-control36(25/11)NGNGACRSkin: endothelial cell, keratinocyteSkin biopsy samples obtained from young, healthy, female volunteers
Kuhn 1998 [22]Case-control26(21/5)NGNGARASkin: keratinocyteNon-lesional skin from healthy people
Gong 2002 [33]Case-control64(34/30)30/429.8ARAPeripheral blood: PBMCHealthy volunteers, mean age was 25.6, gender ratio was 26/4
Xu 2003 [34]Case-control58(38/20)38/032.2ACRPeripheral bloodHealthy volunteers, mean age was 28.2, gender ratio was 20/0
Zheng 2006 [35]Case-control59(49/10)43/630.85ARAKidney: tubular cellNormal kidney biopsies without SLE, but accompanied by renal cell carcinoma
Bollain 2009 [36]Case-control34(17/17)14/325.9ACRkidneyNormal kidney biopsies without renal pathology
  1. F Female, M Male, SLE Systemic lupus erythematosus, ARA American Rheumatism Association, ACR American College of Rheumatology, NG Not given