Skip to main content
Fig. 2 | BMC Immunology

Fig. 2

From: Positive staining of the immunoligand B7-H6 in abnormal/transformed keratinocytes consistently accompanies the progression of cervical cancer

Fig. 2

B7-H6 positivity according to the immunoreactive score in abnormal/transformed cells in cervical precancerous lesions and invasive cervical cancer. The results show a strong positive correlation coefficient between B7-H6 positivity and stage of the disease (LSIL, HSIL, and SCC) (ρ = 0.456), and a significance of p = 0.002. HSIL and both cervical cancer types present significant statistical differences when compared against LSIL. HSIL vs LSIL (p < 0.0005), SCC vs LSIL (p = 0.001) and UCAC vs LSIL (p < 0.0005). No significant differences were found between HSIL and SCC scores, but significance was found when comparing HSIL vs UCAC (p = 0.008), and SCC vs UCAC (p = 0.023). Abbreviations: LSIL: low-grade squamous intraepithelial lesion; HSIL: high-grade squamous intraepithelial lesion; SCC: squamous cervical carcinoma; UCAC: uterine cervical adenocarcinoma. ****p < 0.0005, ***p = 0.001, *p < 0.05

Back to article page

BMC Immunology

ISSN: 1471-2172

Contact us