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Fig. 5 | BMC Immunology

Fig. 5

From: Neutrophil extracellular traps are present in the airways of ENaC-overexpressing mice with cystic fibrosis-like lung disease

Fig. 5

Neutrophil extracellular traps are present in the lungs of βENaC-Tg mice. a Immunofluorescence imaging of histology lung sections obtained from 8 week-old, wild-type and βENaC-Tg 8 mice (40X magnification). Co-localization of DNA (DAPI), MPO, and citrullinated histone 3 (CitH3) identify NETs. Blue=DAPI, orange=MPO, green=CitH3. Scale bars = 50 μm. b A more detailed view of the inset marked as a while square on the βENaC-Tg lung image shown in (a). The white arrow indicates NETs while the white arrow heads point to resting neutrophils characterized by distinct MPO and DNA staining patterns and lack of citrullinated histone staining. Images are representative of one section/ group. Scale bar = 50 μm

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BMC Immunology

ISSN: 1471-2172

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