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Fig. 2 | BMC Immunology

Fig. 2

From: Application of imiquimod-induced murine psoriasis model in evaluating interleukin-17A antagonist

Fig. 2

Characterization and Evaluation of Optimized IMQ-induced Psoriasis Model. a Graphic time-line of modelling. b Upper, typical PASI scoring plot for disease progression; lower, individual scoring for scaling formation, redness and thickness. c Representative images of back skin damage on day 5 of experiment. d Bodyweight change of mice from day 1–7. e Skin thickness change on day 5 of experiment. f Representative Hematoxylin-Erosin (H&E) staining of mice skin on day 7 of experiment. g Representative image of skin damage for model group from three different rounds of experiment. #1, #2 and #3 represents three individual experiment, respectively. Data was expressed as mean ± SEM (n = 6 or 7); *P < 0.05, ***P < 0.001 comparing to model group, Anti-IL17A, Anti-IL17A antibody; Dex, Dexamethasone

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