Skip to main content

Table 2 Physiological, pathological and pharmacological linkages of clinical variables

From: Comprehensive analysis of immunoglobulin and clinical variables identifies functional linkages and diagnostic indicators associated with Behcet’s disease patients receiving immunomodulatory treatment

Type Linkage HC BD-N BD-C BD-I BD-C&I
Pathological linkage A/G-MCH 0.058 0.595 0.491 0.632 0.506
Pathological linkage A/G-MCHC 0.053 0.499 0.779 0.783 0.339
Pathological linkage A/G-PLT − 0.059 − 0.215 − 0.771 − 0.667 − 0.176
Pathological linkage Alb-DBil 0.037 0.116 0.424 0.818 0.192
Pathological linkage Alb-IgG1 0.009 0.42 0.049 0.055 0.335
Pathological linkage Alb-uSG 0.042 0.834 0.584 0.783 0.439
Pathological linkage Cr-upH −0.092 − 0.377 − 0.25 − 0.447 − 0.426
Pathological linkage HGB-TP 0.104 0.256 0.281 0.812 0.345
Pathological linkage IgA2-IgG 0.051 0.493 0.147 0.595 0.209
Pathological linkage IgG-LY% 0.053 0.157 0.28 0.333 0.333
Pathological linkage IgG1-IgG2 0.009 0.304 0.168 0.262 0.481
Pathological linkage LY%-WBC −0.05 − 0.7 − 0.636 − 0.452 − 0.266
Pathological linkage MCH-MONO − 0.061 − 0.266 − 0.671 −0.156 − 0.5
Pathological linkage MCH-PLT −0.069 −0.181 − 0.504 −0.743 − 0.196
Pathological linkage MCHC-PLT −0.042 −0.215 − 0.634 −0.167 − 0.104
Pathological linkage MCV-PLT −0.056 −0.218 − 0.601 −0.539 − 0.22
Pathological linkage PDW-TP −0.006 −0.35 − 0.049 −0.493 − 0.592
Pathological linkage BASO-Cr −0.021 0.365 0.172 0.11 0.37
Pathological linkage BASO-LY% −0.003 0.246 0.244 0.085 0.248
Pathological linkage IgG-MCHC 0.011 −0.293 − 0.445 −0.381 − 0.329
Pathological linkage IgG2-LY −0.074 0.379 0.49 0.262 0.487
Pathological linkage MCHC-MONO 0.077 −0.264 −0.473 − 0.643 −0.613
Pathological linkage upH-TP 0.049 −0.64 − 0.682 − 0.816 − 0.12
Pathological linkage uSG-TP − 0.184 0.781 0.463 0.816 0.439
Pharmacological linkage A/G-PA 0.1286 0.028 0.685 0.377 0.458
Pharmacological linkage A/G-uSG 0.182 0.024 0.425 0.258 0.067
Pharmacological linkage EOS-IgG4 −0.009 −0.014 −0.063 − 0.321 − 0.27
Pharmacological linkage HCT-IgG4 0.244 −0.015 −0.334 − 0.436 −0.109
Pharmacological linkage IgA-IgG4 −0.4763 −0.032 − 0.153 −0.986 − 0.337
Pharmacological linkage IgG-IgG4 0.026 0.007 0.307 0.067 0.271
Pharmacological linkage IgG-LY 0.1786 −0.14 −0.8 −0.551 − 0.394
Pharmacological linkage MCHC-PA −0.4639 −0.027 − 0.338 −0.899 − 0.524
Pharmacological linkage A/G-DBil −0.05007 0.014 0.041 0.841 0.056
Pharmacological linkage A/G-TBil 0.056 0.009 0.402 0.036 0.539
Pharmacological linkage CRP-PLT 0.364 0.032 0.577 0.778 0.518
Pharmacological linkage HGB-MCHC 0.418 0.02 0.149 0.79 0.488
Pharmacological linkage IgG4-TP 0.079 0.093 0.319 0.619 0.444
Pharmacological linkage PDW-TBil 0.143 −0.002 −0.487 −0.143 −0.033
Pharmacological linkage ESR-WBC 0.2504 0.088 0.632 0.771 0.351
Pharmacological linkage IgA-NEUT −0.178 −0.028 −0.6 − 0.108 −0.304
Pharmacological linkage BASO-NEUT 0.113 −0.022 0.36 0.986 0.065
Pharmacological linkage ESR-PA 0.143 −0.042 0.35 0.986 0.341
Pharmacological linkage IgG2-MCHC 0.07099 0.06 −0.61 −0.464 − 0.589
Pharmacological linkage Alb-CRP 0.2121 0.005 −0.874 −0.429 − 0.697
Pharmacological linkage CRP-PA 0.04547 −0.039 0.796 0.314 0.269
Pharmacological linkage IgG-upH −0.1039 0.077 −0.18 −0.486 − 0.176
Pharmacological linkage IgG4-upH −0.118 0.063 −0.216 −0.335 − 0.415
Pharmacological linkage MCHC-WBC −0.2585 0.005 −0.323 −0.272 − 0.237
Pharmacological linkage Alb-PDW 0.276 −0.027 0.616 0.69 0.218
Pharmacological linkage DBil-ESR −0.013 −0.107 0.259 0.333 0.264
Pharmacological linkage ESR-TBil 0.118 0.075 −0.241 − 0.671 −0.256
Pharmacological linkage MCV-MONO 0.124 0.006 −0.633 −0.335 − 0.236
Pharmacological linkage EOS-PA 0.176 −0.095 0.508 0.551 0.331
Pharmacological linkage EOS-upH 0.036 0.005 −0.021 −0.476 − 0.335
Pharmacological linkage ESR-uSG 0.188 −0.021 0.459 0.324 0.047
Pharmacological linkage BASO-LY 0.351 0.439 0.027 0.073 0.216
Pharmacological linkage CRP-MONO 0.4561 0.599 0.116 0.086 0.275
Pharmacological linkage BASO-ESR −0.159 −0.332 −0.014 −0.024 − 0.066
Pharmacological linkage IgG4-NEUT −0.074 0.576 −0.034 −0.044 − 0.027
Pharmacological linkage EOS-IgA 0.2716 −0.631 0.04 0.206 0.042
Pharmacological linkage LY%-PLT −0.012 −0.617 0.065 0.108 0.253
Pharmacological linkage A/G-BASO 0.067 −0.624 0.203 0.252 0.107
Physiological linkage DBil-TBil 0.949 0.968 0.859 0.821 0.9
Physiological linkage HCT-HGB 0.928 0.957 0.977 0.976 0.97
Physiological linkage HCT-RBC 0.898 0.928 0.685 0.929 0.904
Physiological linkage HGB-RBC 0.861 0.879 0.609 0.881 0.844
Physiological linkage IgG-IgG1 0.814 0.621 0.888 0.881 0.878
Physiological linkage MCH-MCV 0.752 0.877 0.932 0.813 0.909
Physiological linkage NEUT-WBC 0.863 0.961 0.895 0.762 0.925
Physiological linkage PCT-PLT 0.933 0.819 0.868 0.732 0.668
Physiological linkage A/G-ESR −0.754 −0.751 −0.956 −0.896 −0.74