Fig. 4

Type 2 diabetic and healthy neutrophils showed differential inflammatory cytokine concentrations across resolvin E1 doses. Human inflammatory cytokine levels (cytokines: MIP-1α, IL-4, IL-8, MIP-1β, P-Selectin, sICAM-1, TNF-α, IL-1α; average pg/mL) in response to resolvin E1 (RvE1) dose, comparing T2D (N = 3) to healthy (N = 3) cultured neutrophils with: A vehicle only (0 nM), B 1 nM, C 10 nM, or D 100 nM RvE1 treatment. For each cytokine, values at or below the lower limit of quantification (LLOQ; based on a 7-standard curve at 1:4 dilution) were reported as the LLOQ value