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Table 1 Clinical demographics of study subjects

From: Transcriptomics of type 2 diabetic and healthy human neutrophils

   Healthy (N = 8) Type 2 Diabetic (N = 13) Total Cohort (N = 21*) p-value
Age (mean in years ± SD)   39 (± 9.63) 58 (± 11.05) 51 (± 14.04) 0.007
Sex (no., %) Male 4 (50%) 7 (53.85%) 11 (52.38%)  
Female 4 (50%) 6 (46.15%) 10 (47.62%)
Ethnicity Caucasian 5 (62.50%) 4 (30.77%) 9 (42.86%)  
Hispanic 0 1 (7.69%) 1 (4.76%)  
African-American 3 (37.50%) 8 (61.54%) 11 (52.38%)
Smoking Status (no., %) Smokers 1 (12.50%) 1 (7.69%) 2 (9.52%)  
Former Smokers 0 2 (15.38%) 2 (9.52%)  
Never Smokers 7 (87.50%) 10 (76.92%) 17 (80.95%)
BMI (kg/m2; mean ± SD)   28.56 (± 4.47) 30.46 (± 6.27) 29.74 (± 5.61) 0.47
Blood Cholesterol (mg/dl; mean ± SD)   144.25 (± 20.61) 183.77 (± 66.97) 168.71 (± 56.80) 0.12
Blood Glucose (mg/dl; mean ± SD) Normal (<  100 mg/dl) 96.50 (± 3.54) 96.50 (± 3.54)  
Pre-diabetes (100-125 mg/dl) 107 (± 3.81) 107 (± 3.81)  
Diabetes (> 126 mg/dl) 209 267.77 (± 123.38) 263.57 (± 119.58) 0.003
HbA1c % (mean ± SD) Normal (<  5.7% HbA1c)  
Pre-diabetes (5.7–6.4% HbA1c) 6.15 (± 0.17) 6.15 (± 0.17)  
Diabetes (>  6.5% HbA1c) 9.64 (± 2.63) 9.64 (± 2.63)
Periodontal Condition (no., %) Healthy 8 (100%) 0 8 (38.09%)  
Mild 0 3 (23.08%) 3 (14.29%)  
Moderate 0 6 (46.15%) 6 (28.57%)  
Severe 0 2 (15.38%) 2 (9.52%)  
Gingivitis 0 2 (15.38%) 2 (9.52%)
Neutrophil Count (mil. of cells, mean ± SD)   104.88 (± 57.23) 123.69 (± 65.68) 116.52 (± 61.83) 0.51
Monocyte Count (mil. of cells, mean ± SD)   72.50 (± 34.13) 99.59 (± 73.72) 89.27 (± 62.05) 0.34
  1. * N = 2 healthy and N = 1 diabetic subjects were included in both the serum and cell culture perturbation analyses. p-values calculated by unpaired t-tests (two-sided p-values; italicized p < 0.05 significant). SD standard deviation, BMI body-mass index