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Table 3 Top over-represented pathways included in pathway analyses

From: Transcriptomics of type 2 diabetic and healthy human neutrophils

Pathway p-value p-value (FDR) p-value (Bonferroni)
KEGG Pathways
 Sphingolipid metabolism 2.52E-04 0.02 0.02
 Ether lipid metabolism 0.004 0.14 0.28
 Phospholipase D signaling pathway 0.02 0.24 1
 Fc gamma R-mediated phagocytosis 0.02 0.24 1
 Glycerophospholipid metabolism 0.02 0.24 1
GO Biological Processes
 Ammonium ion metabolic process 9.30e-5 0.10 0.15
 Surfactant homeostasis 1.20e-4 0.10 0.20
GO Molecular Functions
 Sphingosine-1-phosphate-phosphatase activity 1.20e-4 0.03 0.03
GO Cellular Components
 Plasma membrane 2.00e-4 0.03 0.04
    Integral component of plasma membrane 4.80e-4 0.03 0.11
  1. Uncorrected p-value < 0.05 considered over-represented; Bonferroni or FDR-corrected p-value < 0.05 considered significant. FDR false discovery rate; KEGG Kyoto Encyclopedia of Genes and Genomes; GO Gene Ontology