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Fig. 1 | BMC Immunology

Fig. 1

From: Cisplatin-based chemoradiation decreases telomerase-specific CD4 TH1 response but increases immune suppressive cells in peripheral blood

Fig. 1

Circulating Treg cells before and after CRT. PBMCs from 20 patients treated with CRT for lung or head and neck cancer were taken before CRT and 1 month after. CD4+CD25+CD127lowFoxP3+Treg were analyzed by flow cytometry. A and D Representative plots for Treg (A) and CTLA-4+ Treg (D) in one patient. B and E Treg (B) and CTLA4+ Treg (E) rates variation after CRT, lines in red representing significant increase (> 20%) from baseline (n = 20). C and F Treg (C) and CTLA-4+ Treg (F) rates before and after CRT (n = 20). Results are shown as mean (standard deviation). **, p < 0.005 (Wilcoxon test)

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