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Fig. 4 | BMC Immunology

Fig. 4

From: Type 2 innate lymphoid cells from Id1 transgenic mice alleviate skin manifestations of graft-versus-host disease

Fig. 4

ILC2s from dKO mice have complex effects on aGVDH. Weight loss and GVHD scores of indicated cohorts of transplant recipients. Black circles represent mice that received BM alone (n = 9), red squares represent mice that received BM and sorted T cells (n = 27), and green and blue upward and downward triangles represent the groups that received BM, T cells and ILC2s from dKO mice treated without (n = 17) and with IL-25 (n = 18), respectively. The graphs are as described for Fig. 3. (A) Weight change is shown as a percent of baseline weight. (B) Cumulative GVHD scores are calculated based on weight loss, posture, activity, fur texture and skin integrity with the maximum score being 10. Values represent means and error bars represent the SEM. Two way ANOVA was used for assessing statistical significance. ** p < 0.01, **** p < 0.0001. Data is cumulative of 3 experiments

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