Table 1 The detailed demographic, clinical, and laboratory characteristics of 30 pSS patients
Indexes | RNA sequencing(n = 4) | PCR validation(n = 30) |
|---|---|---|
Sex, no. Male/female | 0/4 | 0/30 |
Age, mean (SD) years | 47.0(12.1) | 52.7 (13.1) |
Disease duration, median (IQR) years | 3.5(1.0) | 1.0(6.2) |
Oral dryness (VAS,1–10), median (IQR) | 5.0(2.0) | 5.5(4.3) |
Ocular dryness (VAS,1–10), median (IQR) | 3.5(1.0) | 3.0(5.3) |
Grading of labial salivary gland biopsies, no. | ||
Grade2, no. | 0 | 1 |
Grade3, no. | 2 | 11 |
Grade4, no. | 2 | 13 |
IgG (g/L), mean ± SD | 14.9(2.5) | 17.5(3.4) |
C3 (g/L), mean ± SD | 0.89(0.24) | 0.83(0.24) |
C4 (g/L), mean ± SD | 154.3(48.1) | 156.8(72.6) |
ESR (mm/h), mean ± SD | 25(19) | 30(45) |
RF (IU/mL), mean ± SD | 12.4(2.7) | 12.7(19.8) |
SSA, no. +/− | 4/0 | 25/5 |
SSB, no. +/− | 1/3 | 8/22 |
B cell, %. median (IQR) | 23.1(8.3) | 18.2(7.8) |
ESSDAI score, median (IQR) | 2.5(1.0) | 3.8(1.9) |