Table 3 Top 15 significantly differential expressed mRNAs between pSS patients and control subjects
up-regulated mRNA | P value | Fold change | down-regulated mRNA | P value | Fold change |
|---|---|---|---|---|---|
MPO | 7.03E-05 | 7.779 | MYOM2 | 1.68E-07 | −9.794 |
SIGLEC1 | 7.42E-08 | 5.642 | SH2D1B | 1.72E-06 | −4.162 |
IFI44L | 1.16E-06 | 5.570 | COL6A2 | 1.68E-06 | −4.160 |
IFI44 | 9.43E-08 | 3.296 | KIR2DL3 | 8.09E-06 | −3.965 |
IFI6 | 1.45E-06 | 2.868 | ARMCX3 | 3.29E-08 | −3.629 |
PCNP | 1.96E-06 | 2.840 | KLRF1 | 2.63E-05 | −3.585 |
CMPK2 | 3.75E-05 | 2.590 | GNLY | 6.24E-05 | −3.580 |
EPSTI1 | 1.42E-07 | 2.559 | PRF1 | 1.75E-05 | −3.406 |
CD83 | 3.75E-07 | 2.557 | APEX1 | 8.96E-06 | −3.370 |
ZNF267 | 1.02E-05 | 2.525 | SPON2 | 8.17E-05 | −3.291 |
PIM3 | 1.12E-04 | 2.460 | FGFBP2 | 1.15E-04 | −3.192 |
U2AF1 | 3.65E-05 | 2.313 | KLRB1 | 1.13E-05 | −2.793 |
SPI1 | 9.36E-06 | 2.290 | CPA3 | 9.46E-05 | −2.754 |
PLSCR1 | 2.90E-06 | 2.282 | IL2RB | 4.00E-05 | −2.471 |
LAP3 | 4.52E-06 | 2.089 | LDLRAP1 | 5.30E-05 | −2.301 |