Fig. 2

The cross-sectional adiponectin and homeostasis model assessment-estimated insulin resistance (HOMA-IR)-centered associations between dependent and independent factors before (pre-therapy) and 24 weeks after DAA therapy (post-therapy). Tips of black arrowheads: dependent factors; bases of black arrowheads: independent factors; GM: HCV genotype; TG: triglycerides; IR: insulin resistance; BMI: body mass index; FIB-4: Fibrosis-4 index; pre-therapy: levels of variables before direct acting antiviral (DAA) therapy; eGFR: estimated glomerular filtration rate; NLR: neutrophil to lymphocyte ratio; ALT: alanine aminotransferase; SVR: sustained virological response. Rising arrow indicates post-therapeutic increases in HOMA-IR (baseline IR = 0, ie. no baseline IR) levels, while descending arrows indicate post-therapeutic decreases in HOMA-IR (baseline IR = 1, ie. with baseline IR) and adiponectin levels