Table 1 Baseline characteristics of the CHC patients
|  | All (n = 427) | Male (n = 195) | Female (n = 232) | p values * |
|---|---|---|---|---|
Age (years) | 61.3 ± 12.8 | 59.1 ± 12.1 | 61.3 ± 12.8 | 0.076 |
BMI (kg/m2) | 24.6 ± 3.9 | 25.1 ± 3.46 | 24.2 ± 4.19 | 0.012 |
HCV genotype | ||||
Genotype 1, n (%) | 256 (59.9) | 116 (59.4) | 140 (60.3) | 0.31 |
Genotype 2, n (%) | 137 (32.0) | 60 (30.7) | 67 (28.8) | 0.95 |
Genotype 3, n (%) | 6 (1.7) | 4 (2) | 2 (0.8) | 0.301 |
Log HCV RNA (logIU/mL) | 5.98 ± 0.87 | 5.96 ± 0.92 | 5.98 ± 0.83 | 0.813 |
ALT (U/L) | 79.8 ± 90.4 | 93.4 ± 108.4 | 68.5 ± 71.6 | 0.006 |
eGFR (mL/min/1.73 m2) | 86.9 ± 41.7 | 89.1 ± 40.5 | 85.0 ± 42.8 | 0.326 |
TG (mg/dL) | 102.6 ± 52.6 | 105.9 ± 58.5 | 99.8 ± 47.1 | 0.235 |
TC (mg/dL) | 169.5 ± 35.3 | 163.7 ± 33.0 | 174.4 ± 36.5 | 0.002 |
Fasting glucose (mg/dL) | 97.79 ± 31.41 | 100.10 ± 39.07 | 96.04 ± 23.96 | 0.066 |
Insulin (μIU/mL) | 10.18 ± 30.01 | 10.53 ± 15.50 | 9.92 ± 37.29 | 0.793 |
HOMA-IR | 3.17 ± 4.88 | 3.72 ± 6.61 | 2.77 ± 2.56 | 0.045 |
Uric acid (mg/dL) | 5.71 ± 1.62 | 6.17 ± 1.69 | 5.28 ± 1.42 |  < 0.001 |
NLR | 1.98 ± 1.24 | 2.06 ± 1.19 | 1.91 ± 1.29 | 0.248 |
Platelet (103/uL) | 176.8 ± 71.7 | 176.8 ± 68.2 | 176.7 ± 74.8 | 0.996 |
Liver cirrhosis, n (%) | 92 (21.5) | 40 (20.9) | 52 (22.4) | 0.699 |
Fibrosis-4 score | 3.53 ± 3.39 | 3.22 ± 3.23 | 3.79 ± 3.51 | 0.083 |
MELD score | 9.08 ± 3.08 | 9.51 ± 4.00 | 8.69 ± 3.62 | 0.022 |
Ferritin (ng/mL) | 376.1 ± 513.2 | 461.7 ± 448.9 | 298.1 ± 555.3 | 0.002 |
Adiponectin (μg/mL) | 6.52 ± 2.71 | 5.87 ± 2.37 | 7.06 ± 2.85 |  < 0.001 |
IFNL3-rs12979860 CC genotype, n (%) | 1018 (84.7) | 166 (85.1) | 195 (84.0) | 0.829 |