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Table 2 Associations of adiponectin levels in CHC patients at baseline

From: Critical role of triglycerides for adiponectin levels in hepatitis C: a joint study of human and HCV core transgenic mice

Baseline factors

Univariate analyses

Multivariate analyses

 

95% CI of β (β)

p values

95% CI of β (β)

p values

Male, yes

− 1.74 to − 0.647 (− 1.194)

 < 0.001

− 1.44 to − 0.417 (− 0.93)

 < 0.001

Age (years)

0.026–0.068 (0.047)

 < 0.001

− 0.039 to 0.015 (− 0.012)

0.394

BMI (kg/m2)

− 0.194 to − 0.159 (− 0.127)

 < 0.001

− 0.098  to  0.052 (− 0.023)

0.545

HCV genotype

− 0.146  to   0.143 (0.014)

0.868

  

Log HCV RNA (logIU/mL)

− 0.507  to  0.176 (− 0.165)

0.342

  

ALT (U/L)

− 0.002  to  0.005 (0.001)

0.376

  

eGFR (mL/min/1.73 m2)

− 0.025  to  − 0.012 (− 0.019)

 < 0.001

− 0.025  to  − 0.008 (− 0.017)

 < 0.001

TG (mg/dL)

− 0.018  to  − 0.008 (− 0.013)

 < 0.001

− 0.015  to  − 0.005 (− 0.01)

 < 0.001

TC (mg/dL)

− 0.004  to  0.013 (− 0.006)

0.183

  

HOMA-IR

− 0.177  to  − 0.005 (− 0.061)

0.034

− 0.052  to  0.053 (0.00)

0.99

Uric acid (mg/dL)

− 0.312  to  0.077 (− 0.117)

0.237

  

NLR

− 0.321  to  0.203 (− 0.059)

0.659

  

Platelet (103/uL)

− 0.013  to  − 0.006 (− 0.009)

 < 0.001

− 0.006  to  0.004 (− 0.001)

0.617

Liver cirrhosis, yes

− 0.391  to  0.948 (0.279)

0.414

  

Fibrosis-4 score

0.17–0.324 (0.247)

 < 0.001

0.08–0.297 (0.188)

0.001

Ferritin (ng/mL)

− 0.001 to 0.000 (0.000)

0.212

  

IFNL3-rs12979860

CC genotype, yes

− 0.471 to 0.421 (0.4752)

0.324

  
  1. CHC: chronic hepatitis C virus infection; CI: confidence interval; BMI: body mass index; HCV: hepatitis C virus; RNA: ribonucleic acid; ALT: alanine transaminase; eGFR: estimated glomerular filtration rate; TG: triglycerides; TC: total cholesterol; HOMA-IR: homeostatic model assessment for insulin resistance; NLR: neutrophil lymphocyte ratio; IFNL3; interferon-λ3