Table 3 Associations of HOMA-IR levels in CHC patients at baseline
Baseline factors | Univariate analyses | Multivariate analyses | ||
|---|---|---|---|---|
|  | 95% CI of β (β) | p values | 95% CI of β (β) | p values |
Male, yes | 0.081–1.964 (1.022) | 0.033 | − 1.44 to − 0.417 (− 0.93) | 0.100 |
Age (years) | − 0.069 to 0.004 (− 0.032) | 0.085 | − 0.039 to 0.015 (− 0.012) | 0.678 |
BMI (kg/m2) | 0.142–0.378 (0.26) |  < 0.001 | 0.029–0.327 (0.178) | 0.02 |
HCV genotype | 1.262–5.513 (3.387) | 0.002 | 0.743–5.279 (3.011) | 0.009 |
Log HCV RNA (logIU/mL) | 0.001 to 1.072 (0.536) | 0.05 | − 0.343 to 0.868 (0.248) | 0.433 |
ALT (U/L) | − 0.136 to 0.162 (0.013) | 0.865 |  |  |
eGFR (mL/min/1.73 m2) | 0.000–0.023 (0.012) | 0.043 | − 0.013 to 0.023 (0.005) | 0.575 |
TG (mg/dL) | 0.015–0.033 (0.024) |  < 0.001 | 0.01–0.03 (0.02) |  < 0.001 |
TC (mg/dL) | − 0.015 to 0.012 (− 0.002) | 0.812 |  |  |
Adiponectin (μg/mL) | − 0.4 to − 0.016 (− 0.208) | 0.034 | − 0.197 to 0.215 (0.009) | 0.932 |
Uric acid (mg/dL) | − 0.141 to 0.541 (0.2) | 0.25 |  |  |
NLR | − 0.275 to 0.573 (0.149) | 0.491 |  |  |
Platelet (103/uL) | − 0.004 to 0.009 (0.002) | 0.489 |  |  |
Liver cirrhosis, yes | − 0.692 to 1.595 (0.451) | 0.438 |  |  |
Fibrosis-4 score | − 0.183 to 0.188 (− 0.048) | 0.49 |  |  |
Ferritin (ng/mL) | 0.000–0.002 (0.001) | 0.027 | 0.000 to 0.002 (0.001) | 0.134 |
IFNL3-rs12979860 CC genotype, yes | − 1.695 to 1.849 (0.077) | 0.932 |  |  |