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Table 7 Associations of adiponectin levels in HCV core transgenic mice

From: Critical role of triglycerides for adiponectin levels in hepatitis C: a joint study of human and HCV core transgenic mice

 

2-month-old DTM

12-month-old DTM

 

95% CI of β (β)

p values

95% CI of β (β)

p values

95% CI of β (β)

p values

95% CI of β (β)

p values

Male, yes

− 2.83 to − 1.07 (− 1.90)

 < 0.001

− 6.954 to − 0.547 (− 3.75)

0.025

− 7.8 to − 2.5 (− 5.2)

0.001

− 5.616 to − 0.50 (− 3.059)

0.023

ALT (U/L)

0.000–0.007 (0.004)

0.041

− 2.37 to 0.039 (− 0.099)

0.144

− 0.035 to 0.025 (− 0.005)

0.29

  

TG (mg/dL)

− 0.056 to 0.048 (− 0.004)

0.866

  

0.054–0.14 (0.097)

 < 0.001

0.021–0.111 (0.066)

0.007

TC (mg/dL)

− 0.136 to 0.007 (− 0.065)

0.073

− 0.172 to 0.107 (− 0.032)

0.622

− 0.147 to 0.043 (− 0.052)

0.257

  

HOMA-IR

− 0.343 to 0.221 (− 0.061)

0.662

  

− 0.891 to 0.493 (− 0.199)

0.536

  
  1. HCV: hepatitis C virus; DTM: tTA-HCV core double transgenic mice; ALT: alanine transaminase; eGFR: estimated glomerular filtration rate; TG: triglycerides; TC: total cholesterol; HOMA-IR: homeostatic model assessment for insulin resistance