Fig. 2
From: Identification of active small-molecule modulators targeting the novel immune checkpoint VISTA
The 3D structural comparison between the human and murine VISTA proteins and their ligand-interacting residues. a The human VISTA protein extracellular domain (green); b The murine VISTA protein extracellular domain (light blue); c Aligned human VISTA protein (green) and murine VISTA protein (light blue); d Ligand interacting residues: murine VISTA antagonist interacting residues (orange), 3D structural alignment of the whole human/murine VISTA protein extracellular domain (bottom right)