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Fig. 3 | BMC Immunology

Fig. 3

From: An efficient method to identify virus-specific TCRs for TCR-T cell immunotherapy against virus-associated malignancies

Fig. 3

A single dominant TCRα chain and TCRβ chain were retrieved from ImmunoSEQ results. Heatmaps of TCR variable gene usage were displayed. For HPV-16-E711–19 specific T cells, the top Vα accounts for 97.74% and the top Vβ accounts for 92.38%. For CMV-pp65495–503 specific T cells, the frequencies of the top Vα and Vβ are 91.62% and 97.15%, respectively. The frequencies of the top Vα and Vβ of EBV-LMP2237–245 specific T cells are 99.9% and 99.64%

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