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Table 4 Cytokine production in indirect contact coculture system response to TLR2 activation (pg/ml)

From: Activation of Toll-like receptor 2 enhances peripheral and tumor-infiltrating CD8+ T cell cytotoxicity in patients with gastric cancer

 

NC (peripheral) (n = 6)

GC (peripheral) (n = 17)

GC (tumor-infiltrating) (n = 17)

− Pam3Csk4

+ Pam3Csk4

− Pam3Csk4

+ Pam3Csk4

− Pam3Csk4

+ Pam3Csk4

IFN-γ

809.2 ± 113.4

880.4 ± 155.3

537.4 ± 100.3#

507.9 ± 90.67

521.7 ± 138.4 #

568.8 ± 99.35

TNF-α

110.3 ± 34.40

102.0 ± 37.79

80.09 ± 11.48#

85.75 ± 10.75

78.88 ± 19.55#

79.89 ± 16.74

IL-2

122.4 ± 38.41

114.1 ± 19.90

93.48 ± 24.61#

89.49 ± 21.78

98.90 ± 29.66#

97.82 ± 28.72

IL-6

87.90 ± 32.24

91.03 ± 26.33

69.37 ± 9.38#

71.81 ± 18.29

66.75 ± 19.22#

64.72 ± 18.39

IL-8

271.96 ± 86.43

272.8 ± 74.72

141.75 ± 28.57#

147.11 ± 23.97

146.1 ± 33.22#

148.0 ± 30.27

  1. #P < 0.05 compared with NC