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Table 1 Percentage positive antibody responses of human sera for peptides that represent E protein epitopes with a pan serotype conservancy more than 50%

From: Natural immunogenic properties of bioinformatically predicted linear B-cell epitopes of dengue envelope and pre-membrane proteins

Peptide ID (location) Sera infected with one serotype Sera infected with two serotypes
DENV1 serotype DENV2 serotype DENV3 serotype DENV4 serotype
P1/E (7–23) 1
8%
0
0%
0
0%
1
8%
0
0%
P2/E (30–46) 12
100%
9
75%
6
50%
0
0%
4
33%
P3/E (60–76) 10
83%
0
0%
9
75%
12
100%
5
42%
P4/E (72–88) 12
100%
12
100%
12
100%
12
100%
11
91%
P5/E (89–104) 12
100%
12
100%
12
100%
12
100%
10
83%
P6/E (110–126) 0
0%
0
0%
0
0%
0
0%
0
0%
P7/E (178–194) 0
0%
0
0%
0
0%
0
0%
0
0%
P8/E (238–254) 0
0%
0
0%
0
0%
0
0%
0
0%
P9/E (255–271) 0
0%
0
0%
0
0%
0
0%
0
0%
P10/E (279–295) 0
0%
0
0%
0
0%
0
0%
0
0%
P11/E (308–324) 6
50%
0
0%
5
42%
0
0%
0
0%
P12/E (371–387) 9
75%
1
8%
9
75%
0
0%
2
17%
P13/E (377–393) 0
0%
12
100%
9
75%
9
75%
6
50%
P14/E (394–410) 10
83%
10
83%
12
100%
12
100%
12
100%
P15/E (418–434) 12
100%
12
100%
12
100%
12
100%
12
100%
P16/E (424–440) 0
0%
12
100%
10
83%
10
83%
5
42%
P17/E (458–474) 10
83%
9
75%
9
75%
9
75%
8
67%
  1. Number of sera samples giving positive responses out of twelve sera samples tested per serotype (DENV1, DENV2, DENV3, DENV4), and its percentage (%) are shown. The number of total tested sera samples infected with two serotypes are also twelve. The corresponding epitope/peptide sequences from cross serotypes are based on the peptide arrays; DENV1 (Singapore/S275/1990 (NR-4551)