Skip to main content

Table 1 Percentage positive antibody responses of human sera for peptides that represent E protein epitopes with a pan serotype conservancy more than 50%

From: Natural immunogenic properties of bioinformatically predicted linear B-cell epitopes of dengue envelope and pre-membrane proteins

Peptide ID (location)

Sera infected with one serotype

Sera infected with two serotypes

DENV1 serotype

DENV2 serotype

DENV3 serotype

DENV4 serotype

P1/E (7–23)

1

8%

0

0%

0

0%

1

8%

0

0%

P2/E (30–46)

12

100%

9

75%

6

50%

0

0%

4

33%

P3/E (60–76)

10

83%

0

0%

9

75%

12

100%

5

42%

P4/E (72–88)

12

100%

12

100%

12

100%

12

100%

11

91%

P5/E (89–104)

12

100%

12

100%

12

100%

12

100%

10

83%

P6/E (110–126)

0

0%

0

0%

0

0%

0

0%

0

0%

P7/E (178–194)

0

0%

0

0%

0

0%

0

0%

0

0%

P8/E (238–254)

0

0%

0

0%

0

0%

0

0%

0

0%

P9/E (255–271)

0

0%

0

0%

0

0%

0

0%

0

0%

P10/E (279–295)

0

0%

0

0%

0

0%

0

0%

0

0%

P11/E (308–324)

6

50%

0

0%

5

42%

0

0%

0

0%

P12/E (371–387)

9

75%

1

8%

9

75%

0

0%

2

17%

P13/E (377–393)

0

0%

12

100%

9

75%

9

75%

6

50%

P14/E (394–410)

10

83%

10

83%

12

100%

12

100%

12

100%

P15/E (418–434)

12

100%

12

100%

12

100%

12

100%

12

100%

P16/E (424–440)

0

0%

12

100%

10

83%

10

83%

5

42%

P17/E (458–474)

10

83%

9

75%

9

75%

9

75%

8

67%

  1. Number of sera samples giving positive responses out of twelve sera samples tested per serotype (DENV1, DENV2, DENV3, DENV4), and its percentage (%) are shown. The number of total tested sera samples infected with two serotypes are also twelve. The corresponding epitope/peptide sequences from cross serotypes are based on the peptide arrays; DENV1 (Singapore/S275/1990 (NR-4551)