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Table 5 The viral neutralization titres of different mice immune sera against different serotypes of DENV

From: Natural immunogenic properties of bioinformatically predicted linear B-cell epitopes of dengue envelope and pre-membrane proteins

Peptide ID (location) DENV 1 DENV 2 DENV 3 DENV 4
Batch 1 Batch 2 Batch 3 Batch 1 Batch 2 Batch 3 Batch 1 Batch 2 Batch 3 Batch 1 Batch 2 Batch 3
POS 203 471 236 490 324 245 236 1027 369 65 249 50
NEG 20 20 20 20 20 20 20 20 20 20 20 20
P4/E
(72–88)
296 321 125 755 797 1250 379 253 218 116 332 185
P5/E
(89–104)
139 171 144 829 506 302 267 276 248 81 164 103
P14/E
(394–410)
81 346 290 286 541 60 56 86 - 100 137 119
P15/E
(418–434)
58 441 749 70 406 344 118 61 968 65 20 794
P17/E
(458–574)
257 212 757 239 486 266 361 145 2453 106 182 366
  1. The virus neutralization titres of different mice immune sera against of the four DENV serotypes are shown in the table. The virus neutralization titre is the serum dilution at which 50% virus neutralization (EC50). The percentage of virus neutralization is calculated by taking the reduction in the virus titre in the presence of a given immunesera as compared to the virus titre in the absence of immunesera
  2. POS, positive control (the entire DENV E protein). NEG, negative control (PBS and adjuvant); Batch 1–3, different batches of mice