Fig. 7
From: Dimethyl itaconate alleviates the pyroptosis of macrophages through oxidative stress
Effect of NAC on DI treatment of LPS + ATP-induced pyroptosis of BMDMs. a Cell mortality was observed by fluorescence microscopy after PI staining. b The cell number was quantified by counting in three random at 10×, and the mortality was expressed as mean ± SEM. c The concentrations of ROS were detected by the DCFH-DA and expressed as fluorescence value. d The concentration of IL-1β was detected by ELISA. (n = 3 per group, ##P < 0.005, ####P < 0.0001 compared to the DI + LPS + ATP group)