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Table 4 Correlations between clinicopathological data and glomerular IgM deposition in lupus nephritis

From: Clinical relevance of glomerular IgM deposition in patients with lupus nephritis

Parameters

r

P value

Clinical parameters

 Age (years)

− 0.154

0.024

 SLEDAI

0.013

0.847

 Hemoglobin (g/L)

0.008

0.907

 24-h urine protein (g/24 h)

0.050

0.466

 Serum creatinine (μmol/L)

− 0.039

0.572

 Plasma C1q levels (mg/L)

− 0.109

0.115

 Plasma C3 levels (g/L)

− 0.138

0.043

 Plasma CFH levels (μg/mL)

− 0.147

0.037

 Plasma soluble C5b-9 levels (ng/mL)

0.009

0.899

Pathological parameters

 Histological classes

− 0.010

0.882

 AI

0.003

0.965

 Endocapillary hypercellularity

0.050

0.461

 Cellular crescents

− 0.064

0.345

 Karyorrhexis/fibrinoid necrosis

0.024

0.720

 Subendothelial hyaline deposits

0.136

0.045

 Interstitial inflammatory cell infiltration

− 0.153

0.025

 Glomerular leukocyte infiltration

− 0.005

0.943

 CI

− 0.022

0.745

 Glomerular sclerosis

− 0.014

0.843

 Fibrous crescents

− 0.012

0.860

 Tubular atrophy

− 0.033

0.626

 Interstitial fibrosis

− 0.062

0.360

 Glomerular IgG deposition

0.293

< 0.001

 Glomerular IgA deposition

0.456

< 0.001

 Glomerular C3 deposition

0.436

< 0.001

 Glomerular C1q deposition

0.408

< 0.001

  1. CFH complement factor H, SLEDAI Systemic Lupus Erythematosus Disease Activity Index, AI activity indices, CI chronicity indices