CD4, CD8 and natural killer cells are depressed in patients with alopecia areata: their association with disease activity

Table 3 Comparison between laboratory parameters of alopecia areata patients and healthy control subjects

Laboratory parameters	Alopecia areata	Control	P value
Patients, n	50	50
WBCs 10^3/mm³	6.90 ± 1.63	6.00 ± 1.08	0.001*
Neutrophil (%)	59.77 ± 7.31	58.73 ± 4.19	0.383
Neutrophil count 10^3/mm³	4.60 ± 1.21	4.29 ± 0.69	0.121
Lymphocyte (%)	38.09 ± 7.59	35.34 ± 3.56	0.022*
Lymphocytes count 10^3/mm³	2.36 ± 0.55	2.14 ± 0.42	0.029*
NLR	2.06 ± 0.80	2.09 ± 0.58	0.818
Monocytes count 10^3/mm³	0.20 ± 0.06	0.22 ± 0.10	0.097
Monocytes (%)	3.61 ± 1.43	4.07 ± 0.99	0.065
LMR	13.18 ± 5.44	10.99 ± 3.94	0.023*
CD4⁺ T cells (%)	33.95 ± 11.19	40.32 ± 6.42	0.001*
CD8⁺ T cells (%)	23.38 ± 7.06	31.08 ± 5.05	< 0.001*
CD4⁺/CD8⁺ ratio	1.52 ± 0.33	1.31 ± 0.22	0.001*
CD56 bright CD16⁻ (%)	1.46 ± 0.57	1.81 ± 0.79	0.012*
CD56 bright CD16 ⁺ (%)	10.10 ± 8.02	7.94 ± 4.02	0.092
CD56 ⁻ CD16 ⁺ (%)	6.62 ± 3.01	5.69 ± 2.16	0.081

WBCs, white blood cells; RBCs, red blood cells; NLR, neutrophil- lymphocytes ratio; LMR, lymphocyte-monocyte ratio; CD, cluster of differentiation
Values are expressed as means ± SD
*P value < 0.05 was considered statistically significant

ISSN: 1471-2172