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Fig. 2 | BMC Immunology

Fig. 2

From: Helios expressing regulatory T cells are correlated with decreased IL-2 producing CD8 T cells and antibody diversity in Mozambican individuals living chronically with HIV-1

Fig. 2

Correlations between the number of HIV-1 antigens recognized by antibodies and immune restoration indicators. PBMC and whole blood from PLWH-C (n = 20) were stained with monoclonal antibodies and analyzed by polychromatic flow cytometry. Serum antibody reactivity to HIV-1 – Env (gp160 and gp41), Gag (p24) and Pol (p31) proteins was analyzed on stored serum samples from all individuals living with HIV-1, using immuno-chromatographic test as described in Methods section. Correlations between the number (#) of HIV-1 antigens recognized by antibodies/ seroreactivity to HIV-1 proteins and (a) activation of CD8 T cells, (b) viral load and (c) absolute CD4 T cell counts in PLWH-C. Each point corresponds to one individual. Spearman’s correlation r and p-values are indicated on each figure

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BMC Immunology

ISSN: 1471-2172

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