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Fig. 3 | BMC Immunology

Fig. 3

From: Helios expressing regulatory T cells are correlated with decreased IL-2 producing CD8 T cells and antibody diversity in Mozambican individuals living chronically with HIV-1

Fig. 3

Correlations between Tregs and cytokine-producing CD4 and CD8 T cells, CD4 T cell absolute counts and viral loads. PBMC from PLWH-C were isolated and treated as described in Methods section. PBMC were stained with monoclonal antibodies and analyzed by polychromatic flow cytometry. Absolute counts of CD4 T cells were determined using a four-color flow cytometer as described in the methods section. Correlation between the proportion of Tregs and a frequency of CD4 T cells expressing IL-2 (n = 21) PLWH-C and b frequency of CD8 T cell expressing IL-2 combined with IFNγ (n = 19) PLWH-C. c Correlation between the proportions of Tregs within CD4 T cells and viral load (n = 18) and d CD4 T cells absolute counts in PLWH without VS (n = 18). e Correlation between the proportions of Tregs and CD4 T cells absolute counts in PLWH-C with VS (n = 9)

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