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Fig. 6 | BMC Immunology

Fig. 6

From: Exhausted phenotype of circulating CD8+ T cell subsets in hepatitis B virus carriers

Fig. 6

The Tfc subset possessed higher effector functions than the Tc subset in HBV carriers. A Flow cytometric detection of IFN-γ, TNF-α, Granzyme B, and CD107a expression on CD8+ T cells among PBMCs from HCs and HBV carriers; B differential production of effector cytokines by CD8+ T cells between HCs (n = 15) and HBV carriers (n = 15); C flow cytometric detection of effector cytokines in the Tfc and Tc subsets in HBV carriers; D paired analysis of cytokine expression in the Tfc and Tc subsets in HBV carriers. HCs: healthy controls, HBV: hepatitis B virus, Tfc: follicular cytotoxic T cells (CXCR5+FOXP3−), Tc: cytotoxic T cells (CXCR5−FOXP3−); data are presented as the means ± SEs; **P < 0.01

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