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Table 2 Comparison of the frequency of HLA-DRB1 alleles in OBI carriers and control group at high resolution

From: High resolution HLA-DRB1 analysis and shared molecular amino acid signature of DRβ1 molecules in Occult hepatitis B infection

 

OBI (GF%)

Control (GF%)

P value

Pc value

OR

95% CI

HLA

2n = 214

2n = 560

    

DRB1*01:01

0.47

2.86

0.042

1.764

0.160

0.021–1.211

DRB1*01:02

0.47

0.36

DRB1*03:01

4.67

4.46

0.901

DRB1*04:01

0.00

1.43

DRB1*04:03

0.93

1.43

DRB1*04:04

0.47

0.71

DRB1*04:05

3.27

4.64

0.398

DRB1*04:06

1.40

3.04

0.200

DRB1*04:07

0.47

0.18

DRB1*04:08

0.93

0.18

DRB1*04:10

0.00

0.71

DRB1*07:01

19.16

10.54

0.001

0.042

2.012

1.303–3.107

DRB1*08:01

0.47

0.00

DRB1*08:02

0.47

1.07

DRB1*08:03

2.34

5.71

0.049

2.058

0.395

0.152–1.027

DRB1*08:09

0.47

0.18

DRB1*09:01

16.36

12.86

0.207

DRB1*10:01

0.47

1.79

  

DRB1*11:01

7.48

5.36

0.265

DRB1*11:03

0.00

0.18

DRB1*11:04

0.47

2.32

0.128

DRB1*12:01G

6.07

5.18

0.623

DRB1*12:02

10.28

8.04

0.321

DRB1*13:01

0.93

1.61

DRB1*13:02

0.93

2.68

0.176

DRB1*13:05

0.47

0.00

DRB1*13:07

0.00

0.18

DRB1*13:12

0.47

0.18

DRB1*13:49

0.47

0.00

DRB1*14:03

0.93

0.18

DRB1*14:04

0.00

0.71

DRB1*14:05

4.21

1.96

0.079

DRB1*14:07

0.00

0.18

DRB1*14:09

0.47

0.00

DRB1*14:11

0.00

0.18

DRB1*14:12

0.00

0.18

DRB1*14:25

0.00

0.18

DRB1*14:54

1.40

2.68

0.292

DRB1*15:01

5.61

10.71

0.029

1.218

0.495

0.261–0.940

DRB1*15:02

3.74

3.04

0.621

DRB1*15:04

1.87

0.00

DRB1*16:02

1.40

2.14

0.504

  1. OBI, occult hepatitis B infection; GF, gene frequency; OR, odds ratio; 95%CI, 95% confidence interval; Pc, corrected P
  2. Only alleles with > 2% frequencies in either group were shown analyzed. – indicated the allele frequency < 2% were not analyzed, or P > 0.05, Pc were not calculated. In bold: significant value of Pc < 0.05